Product claims may differ from country to country based on regulations and product approvals. Please contact your country representative for further details.

Publikationsliste

Hier sehen Sie unsere aktuellen Publikationen gegliedert nach Indikationsgebieten.

Weitere Informationen zu unseren aktuellen Forschungsarbeiten erhalten Sie von Frau Claudia Kohlbrenner: claudia.kohlbrenner@thermofisher.com

Über eine Auswahl einer Unterkategorie können Sie die Suche starten:

 

Infektion
 
 
  
Hartmann O, Schuetz P, Albrich WC, Anker SD, Mueller B, Schmidt T.
Time-dependent Cox regression: Serial measurement of the cardiovascular biomarker proadrenomedullin improves survival prediction in patients with lower respiratory tract infection.
Int J Cardiol. 2012 Nov 29;161(3):166-73


Boeck L, Eggimann P, Smyrnios N, Pargger H, Thakkar N, Siegemund M, Morgenthaler NG, Rakic J, Tamm M, Stolz D.
The Sequential Organ Failure Assessment score and copeptin for predicting survival in ventilator-associated pneumonia.
J Crit Care. 2012 Oct;27(5):523.e1-9.



Schulte J.
Peroxiredoxin 4: a multifunctional biomarker worthy of further exploration.
BMC Med. 2011 Dec 23;9(1):137.

Krüger S, Ewig S, Giersdorf S, Hartmann O, Suttorp N, Welte T; the CAPNETZ study group.
Cardiovascular and Inflammatory Biomarkers to Predict Short- and Long-term Survival in Community-acquired Pneumonia.
Am J Respir Crit Care Med. 2010 Dec 1;182(11):1426-1434.


Krüger S, Ewig S, Kunde J, Hartmann O, Marre R, Suttorp N, Welte T; on behalf of the CAPNETZ study group.
Assessment of inflammatory markers in patients with community-acquired pneumonia - Influence of antimicrobial pre-treatment Results from the German competence network CAPNETZ.
Clin Chim Acta. 2010 Dec 14;411(23-24):1929-34. 


Torgersen C, Luckner G, Morgenthaler NG, Jochberger S, Schmittinger CA, Wenzel V, Hasibeder WR, Grander W, Dünser MW.
Plasma copeptin levels before and during exogenous arginine vasopressin infusion in patients with advanced vasodilatory shock.
Minerva Anestesiol. 2010 Nov;76(11):905-12.




Abbasi A, Corpeleijn E, Postmus D, Gansevoort RT, de Jong PE, Gans RO, Struck J, Hillege HL, Stolk RP, Navis G, Bakker SJ.
Plasma Procalcitonin Is Associated with Obesity, Insulin Resistance, and the Metabolic Syndrome.
J Clin Endocrinol Metab. 2010 Sep;95(9):e26-31.



Limper M, Goeijenbier M, Wagenaar JF, Gasem MH, Isbandrio B, Kunde J, Hartmann O, Duits AJ, Van Gorp EC.
Copeptin as a predictor of disease severity and survival in leptospirosis.
J Infect. 2010 Jul;61(1):92-4.


 
 
Vasoactive mediators in patients with acute liver failure treated with albumin dialysis.
Liver Int. 2010 Apr;30(4):634-6.


Krüger S, Ewig S, Kunde J, Hartmann O, Suttorp N, Welte T; CAPNETZ Study Group.
Pro-atrial natriuretic peptide and pro-vasopressin for predicting short-term and long-term survival in community-acquired pneumonia: results from the German Competence Network CAPNETZ.
Thorax. 2010 Mar;65(3):208-14.


Huang DT, Angus DC, Kellum JA, Pugh NA, Weissfeld LA, Struck J, Delude RL, Rosengart MR, Yealy DM.
Midregional Proadrenomedullin as a Prognostic Tool in Community-Acquired Pneumonia.
Chest. 2009 Sep;136(3):823-31.


Krüger S, Ewig S, Papassotiriou J, Kunde J, Marre R, von Baum H, Suttor N, Welte T; CAPNETZ Study Group.
Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients with CAP: results from the German competence network CAPNETZ.
Respir Res. 2009 Jul 12;10:65.


Potocki M, Breidthardt T, Reichlin T, Morgenthaler NG, Bergmann A, Noveanu M, Schaub N, Uthoff H, Freidank H, Buser L, Bingisser R, Christ M, Mebazaa A, Mueller C.
Midregional pro-Adrenomedullin in addition to B-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study.
Crit Care. 2009 Jul 23;13(4):R122.


Jochberger S, Velik-Salchner C, Mayr VD, Luckner G, Wenzel V, Falkensammer G, Ulmer H, Morgenthaler N, Hasibeder W, Dünser MW.
The vasopressin and copeptin response in patients with vasodilatory shock after cardiac surgery: a prospective, controlled study.
Intensive Care Med. 2009 Mar;35(3):489-97


Bhandari SS, Loke I, Davies JE, Squire IB, Struck J, Ng LL.
Gender and renal function influence plasma levels of copeptin in healthy individuals.
Clin Sci (Lond). 2009 Feb;116(3):257-63


Jochberger S, Zitt M, Luckner G, Mayr VD, Wenzel V, Ulmer H, Morgenthaler NG, Hasibeder WR, Dünser MW.
Postoperative vasopressin and copeptin levels in noncardiac surgery patients: a prospective controlled trial.
Shock. 2009 Feb;31(2):132-8


Jochberger S, Dörler J, Luckner G, Mayr VD, Wenzel V, Ulmer H, Morgenthaler NG, Hasibeder WR, Dünser MW.
The vasopressin and copeptin response to infection, severe sepsis, and septic shock.
Crit Care Med. 2009 Feb;37(2):476-82



Seligman R, Papassotiriou J, Morgenthaler NG, Meisner M, Teixeira PJ.
Prognostic value of midregional pro-atrial natriuretic peptide in ventilator-associated pneumonia.
Intensive Care Med. 2008 Nov;34(11):2084-91


Stolz D, Christ-Crain M, Morgenthaler NG, Miedinger D, Leuppi J, Müller C, Bingisser R, Struck J, Müller B, Tamm M.
Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD.
Chest. 2008 Aug;134(2):263-72


Schuetz P, Stolz D, Mueller B, Morgenthaler N, Struck J, Mueller C, Bingisser R, Tamm M, Christ-Crain M.
Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia.
BMC Infect Dis. 2008 Feb 28;8(1):22

 
de Kruif MD, Lemaire LC, Giebelen IA, Struck J, Morgenthaler NG, Papassotiriou J, Elliott PJ, van der Poll T.
The influence of corticosteroids on the release of novel biomarkers in human endotoxemia.
Intensive Care Med. 2008 Mar;34(3):518-22



Morgenthaler NG, Struck J, Jochberger S, Dünser MW.
Copeptin: clinical use of a new biomarker.
Trends Endocrinol Metab. 2008 Mar;19(2):43-9



Seligman R, Papassotiriou J, Morgenthaler NG, Meisner M, Teixeira PJ.
Copeptin, a novel prognostic biomarker in ventilator-associated pneumonia.
Crit Care. 2008 Jan 24;12(1):R11



Schuetz P, Christ-Crain M, Morgenthaler NG, Struck J, Bergmann A, Müller B.
Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis.
Endothelium. 2007 Nov-Dec;14(6):345-51




Masiá M, Papassotiriou J, Morgenthaler NG, Hernández I, Shum C, Gutiérrez F.
Midregional ProA-Type Natriuretic Peptide and Carboxy-Terminal Provasopressin May Predict Prognosis in Community-Acquired Pneumonia.
Clin Chem. 2007 Dec;53(12):2193-201



Krüger S, Papassotiriou J, Marre R, Richter K, Schumann C, von Baum H, Morgenthaler NG, Suttorp N, Welte T; CAPNETZ Study Group.
Pro-atrial natriuretic peptide and pro-vasopressin to predict severity and prognosis in community-acquired pneumonia : Results from the German competence network CAPNETZ.
Intensive Care Med. 2007 Dec;33(12):2069-78


Krüger S, Ewig S, Marre R, Papassotiriou J, Richter K, von Baum H, Suttorp N, Welte T; the CAPNETZ study group.
Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes.
Eur Respir J. 2008 Feb;31(2):349-55



Prat C, Lacoma A, Dominguez J, Papassotiriou J, Morgenthaler NG, Andreo F, Tudela P, Ruiz-Manzano J, Ausina V.
Midregional pro-atrial natriuretic peptide as a prognostic marker in pneumonia.
J Infect. 2007 Nov;55(5):400-7


Morgenthaler NG, Müller B, Struck J, Bergmann A, Redel H, Christ-Crain M.
Copeptin, a stabel peptide of the arginine vasopressin (AVP) precursor, is elevated in hemorrhagic and septic shock.
Shock, Aug 2007, 28(2),219-226

 
 
Stolz D, Christ-Crain M, Morgenthaler NG, Leuppi J, Miedinger D, Bingisser R, Muller C, Struck J, Muller B, Tamm M.
Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPD.
Chest. 2007 Apr;131(4):1058-67
 
Circulating levels of copeptin, a novel biomarker, in lower respiratory tract infections.
Eur J Clin Invest. 2007 Feb;37(2):145-52
 
Circulating levels of pro-atrial natriuretic peptide in lower respiratory tract infections.
J Intern Med. 2006 Dec;260(6):568-76
 
 
Copeptin and arginine vasopressin concentrations in critically ill patients.
J Clin Endocrinol Metab. 2006 Nov;91(11):4381-6
 
 
Detection of serum neopterin for early assessment of dengue virus infection.
J Infect. 2006 Sep;53(3):152-8
 
Course of vasopressin and copeptin plasma concentrations in a patient with severe septic shock.
Anaesth Intensive Care. 2006 Aug;34(4):498-500
 
Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia.
Crit Care. 2006;10(3):R96
 
 
Proteolytic processing pattern of the endothelin-1 precursor in vivo.
Peptides. 2005 Dec;26(12):2482-6
 
Copeptin, a stable peptide derived from the vasopressin precursor, is elevated in serum of sepsis patients.
Peptides. 2005 Dec;26(12):2500-4
 
 
Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study.
Crit Care. 2005;9(6):R816-24
 
Serum neopterin for early assessment of severity of severe acute respiratory syndrome.
Clin Immunol. 2005 Jul;116(1):18-26
 
 
Release of the mitochondrial enzyme carbamoyl phosphate synthase under septic conditions.
Shock. 2005 Jun;23(6):533-8
 
 
Pro-atrial natriuretic peptide is a prognostic marker in sepsis, similar to the APACHE II score: an observational study.
Crit Care. 2005 Feb;9(1):R37-45
 
 
Identification of an Adrenomedullin precursor fragment in plasma of sepsis patients.
Peptides. 2004 Aug;25(8):1369-72
 
 
Production of procalcitonin (PCT) in non-thyroidal tissue after LPS injection.
Horm Metab Res. 2003 May;35(5):290-5
 
 
Pathobiochemistry and clinical use of procalcitonin.
Clin Chim Acta. 2003 Feb;328(1-2):199
 
 
Detection of procalcitonin (PCT) in healthy controls and patients with local infection by a sensitive ILMA.
Clin Lab. 2002;48(5-6):263-70
 
 
High concentrations of procalcitonin but not mature calcitonin in normal human milk.
Horm Metab Res. 2002 Aug;34(8):460-5
 
Decrease of serum dipeptidylpeptidase activity in severe sepsis patients: relationship to procalcitonin.
Clin Chim Acta. 2002 Jul;321(1-2):123-6

 

 
Kardiologie

Afzali D, Erren M, Pavenstädt HJ, Vollert JO, Hertel S, Waltenberger J, Reinecke H, Lebiedz P.
Impact of copeptin on diagnosis, risk stratification, and intermediate-term prognosis of acute coronary syndromes.
Clin Res Cardiol. 2013 Oct;102(10):755-63.




Möckel M, Searle J, Hartmann O, Anker SD, Peacock WF, Wu AH, Maisel A; on behalf of the BACH Writing group.
Mid-regional pro-adrenomedullin improves disposition strategies for patients with acute dyspnoea: results from the BACH trial.
Emerg Med J. 2013 Aug;30(8):633-7


Maisel A, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke G, Daniels LB, Hollander JE, Apple FS, Cannon C, Nagurney JT, Schreiber D, Defilippi C, Hogan C, Diercks DB, Stein JC, Headden G, Limkakeng AT Jr, Anand I, Wu AH, Papassotiriou J, Hartmann O, Ebmeyer S, Clopton P, Jaffe AS, Peacock WF.
Copeptin Helps in the Early Detection of Patients With Acute Myocardial Infarction: Primary Results of the CHOPIN Trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction).
J Am Coll Cardiol. 2013 Jul 9;62(2):150-60.


Annborn M, Dankiewicz J, Erlinge D, Hertel S, Rundgren M, Smith JG, Struck J, Friberg H.
Procalcitonin after cardiac arrest - An indicator of severity of illness, ischemia-reperfusion injury and outcome.
Resuscitation. 2013 Jun;84(6):782-7


van Hateren KJ, Landman GW, Kleefstra N, Groenier KH, Struck J, Navis GJ, Bakker SJ, Houweling ST, van der Meer K, Bilo HJ.
The Midregional Fragment of Pro-A-Type Natriuretic Peptide, Blood Pressure, and Mortality in a Prospective Cohort Study of Patients With Type 2 Diabetes (ZODIAC-25).
Diabetes Care. 2013 May;36(5):1347-52


Kollerits B, Sturm G, Lamina C, Hammerer-Lercher A, Rantner B, Stadler M, Ziera T, Struck J, Klein-Weigel P, Fraedrich G, Kronenberg F.
Comparison and Evaluation of Cardiac Biomarkers in Patients with Intermittent Claudication: Results from the CAVASIC Study.
Clin Chem. 2013 Apr;59(4):692-702


Tzikas S, Keller T, Ojeda FM, Zeller T, Wild PS, Lubos E, Kunde J, Baldus S, Bickel C, Lackner KJ, Münzel TF, Blankenberg S.
MR-proANP and MR-proADM for risk stratification of patients with acute chest pain.
Heart. 2013 Mar;99(6):388-95


Miller WL, Grill DE, Struck J, Jaffe AS.
Association of Hyponatremia and Elevated Copeptin With Death and Need for Transplantation in Ambulatory Patients With Chronic Heart Failure.
Am J Cardiol. 2013 Mar 15;111(6):880-5



Bhandari SS, Davies JE, Struck J, Ng LL.
The diagnostic performance of mid-regional portion of pro-atrial natriuretic peptide for the detection of left ventricular hypertrophy in Caucasian hypertensive patients.
J Hum Hypertens. 2012 Dec;26(12):711-5


von Haehling S, Papassotiriou J, Morgenthaler NG, Hartmann O, Doehner W, Stellos K, Wurster T, Schuster A, Nagel E, Gawaz M, Bigalke B.
Copeptin as a prognostic factor for major adverse cardiovascular events in patients with coronary artery disease.
Int J Cardiol. 2012 Dec 15;162(1):27-32.


Drion I, Kleefstra N, Landman GW, Alkhalaf A, Struck J, Groenier KH, Bakker SJ, Bilo HJ.
Plasma COOH-Terminal Proendothelin-1: A marker of fatal cardiovascular events, all-cause mortality, and new-onset albuminuria in type 2 diabetes? (ZODIAC-29).
Diabetes Care. 2012 Nov;35(11):2354-8



Schiopu A, Hedblad B, Engström G, Struck J, Morgenthaler NG, Melander O.
Plasma procalcitonin and the risk of cardiovascular events and death: a prospective population-based study.
J Intern Med. 2012 Nov;272(5):484-91


von Haehling S, Papassotiriou J, Hartmann O, Doehner W, Stellos K, Geisler T, Wurster T, Schuster A, Botnar RM, Gawaz M, Bigalke B.
Midregional pro-atrial natriuretic pepide as a prognostic marker for all-cause mortality in patients with symptomatic coronary artery disease.
Clin Sci (Lond). 2012 Nov 1;123(10):601-10


Abbasi A, Corpeleijn E, Postmus D, Gansevoort RT, de Jong PE, Gans RO, Struck J, Schulte J, Hillege HL, van der Harst P, Peelen LM, Beulens JW, Stolk RP, Navis G, Bakker SJ.
Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality.
J Am Heart Assoc. 2012 Oct;1(5):e002956.


Eckstein J, Potocki M, Murray K, Breidthardt T, Ziller R, Mosimann T, Klima T, Hoeller R, Moehring B, Sou SM, Rubini Gimenez M, Morgenthaler NG, Mueller C.
Direct comparison of mid-regional pro-atrial natriuretic peptide with N-terminal pro B-type natriuretic peptide in the diagnosis of patients with atrial fibrillation and dyspnoea.
Heart. 2012 Oct;98(20):1518-22.


Wu AH, Tabas J, Stein J, Potocki M, Mueller C, McCord J, Richards M, Hartmann O, Nowak R, Peacock WF, Ponikowski P, Moeckel M, Hogan C, Filippatos GS, Di Somma S, Anand I, Ng L, Neath SX, Christenson R, Morgenthaler NG, Anker SD, Maisel AS.
The effect of diabetes on the diagnostic and prognostic performance of mid-region pro-atrial natriuretic peptide and mid-region pro-adrenomedullin in patients with acute dyspnea.
Biomarkers. 2012 Sep;17(6):490-7.


Shah RV, Truong QA, Gaggin HK, Pfannkuche J, Hartmann O, Januzzi JL Jr.
Mid-regional pro-atrial natriuretic peptide and pro-adrenomedullin testing for the diagnostic and prognostic evaluation of patients with acute dyspnoea.
Eur Heart J. 2012 Sep;33(17):2197-205.



Brouwers FP, de Boer RA, van der Harst P, Struck J, de Jong PE, de Zeeuw D, Gans RO, Gansevoort RT, Hillege HL, van Gilst WH, Bakker SJ.
Influence of age on the prognostic value of mid-regional pro-adrenomedullin in the general population.
Heart. 2012 Sep;98(18):1348-53.


Schnabel RB, Wild PS, Schulz A, Zeller T, Sinning CR, Wilde S, Kunde J, Lubos E, Lackner KJ, Warnholtz A, Gori T, Blankenberg S, Munzel T; for the Gutenberg Health Study Investigators.
Multiple Endothelial Biomarkers and Noninvasive Vascular Function in the General Population: The Gutenberg Health Study.
Hypertension. 2012 Aug;60(2):288-295.



Miller WL, Hartman KA, Grill DE, Struck J, Bergmann A, Jaffe AS.
Serial measurements of midregion proANP and copeptin in ambulatory patients with heart failure: incremental prognostic value of novel biomarkers in heart failure.
Heart. 2012 Mar;98(5):389-94.


Fedorowski A, Ostling G, Persson M, Struck J, Engström G, Nilsson PM, Hedblad B, Melander O.
Orthostatic blood pressure response, carotid intima-media thickness, and plasma fibrinogen in older nondiabetic adults.
J Hypertens. 2012 Mar;30(3):522-9.


Maisel A, Neath SX, Landsberg J, Mueller C, Nowak RM, Peacock WF, Ponikowski P, Möckel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng LL, Daniels LB, Christenson RH, Potocki M, McCord J, Terracciano G, Hartmann O, Bergmann A, Morgenthaler NG, Anker SD.
Use of procalcitonin for the diagnosis of pneumonia in patients presenting with a chief complaint of dyspnoea: results from the BACH (Biomarkers in Acute Heart Failure) trial.
Eur J Heart Fail. 2012 Mar;14(3):278-86


Magnusson M, Jujic A, Hedblad B, Engström G, Persson M, Struck J, Morgenthaler NG, Nilsson P, Newton-Cheh C, Wang TJ, Melander O.
Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study.
J Clin Endocrinol Metab. 2012 Feb;97(2):638-45.


Daniels LB, Clopton P, Potocki M, Mueller C, McCord J, Richards M, Hartmann O, Anand IS, Wu AH, Nowak R, Peacock WF, Ponikowski P, Mockel M, Hogan C, Filippatos GS, Di Somma S, Ng L, Neath SX, Christenson R, Morgenthaler NG, Anker SD, Maisel AS.
Influence of age, race, sex, and body mass index on interpretation of midregional pro atrial natriuretic peptide for the diagnosis of acute heart failure: results from the BACH multinational study.
Eur J Heart Fail. 2012 Jan;14(1):22-31.


Nickel CH, Bingisser R, Morgenthaler NG.
The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department.
BMC Med. 2012 Jan 20;10(1):7.





Wild PS, Schnabel RB, Lubos E, Zeller T, Sinning CR, Keller T, Tzikas S, Lackner KJ, Peetz D, Rupprecht HJ, Bickel C, Morgenthaler NG, Papassotiriou J, Tiret L, Münzel T, Blankenberg S.
Midregional Proadrenomedullin for Prediction of Cardiovascular Events in Coronary Artery Disease: Results from the AtheroGene Study.
Clin Chem. 2012 Jan;58(1):226-36.



van Hateren KJ, Alkhalaf A, Kleefstra N, Groenier KH, de Jong PE, de Zeeuw D, Gans RO, Struck J, Bilo HJ, Gansevoort RT, Bakker SJ.
Comparison of midregional pro-a-type natriuretic Peptide and the N-terminal pro-B-type natriuretic Peptide for predicting mortality and cardiovascular events.
Clin Chem. 2012 Jan;58(1):293-7


Schulte J.
Peroxiredoxin 4: a multifunctional biomarker worthy of further exploration.
BMC Med. 2011 Dec 23;9(1):137.




Gu YL, Voors AA, Zijlstra F, Hillege HL, Struck J, Masson S, Vago T, Anker SD, van den Heuvel AF, van Veldhuisen DJ, de Smet BJ.
Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction.
Clin Res Cardiol. 2011 Dec;100(12):1069-76.






Colson PH, Bernard C, Struck J, Morgenthaler NG, Albat B, Guillon G.
Post cardiac surgery vasoplegia is associated with high preoperative copeptin plasma concentration.
Crit Care. 2011 Oct 25;15(5):R255.








Maisel A, Mueller C, Nowak RM, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu AH, Richards M, Clopton P, Filippatos GS, Di Somma S, Anand I, Ng LL, Daniels LB, Neath SX, Christenson R, Potocki M, McCord J, Hartmann O, Morgenthaler NG, Anker SD.
Midregion Prohormone Adrenomedullin and Prognosis in Patients Presenting With Acute Dyspnea Results From the BACH (Biomarkers in Acute Heart Failure) Trial.
J Am Coll Cardiol. 2011 Aug 30;58(10):1057-67.


Enhörning S, Struck J, Wirfält E, Hedblad B, Morgenthaler NG, Melander O.
Plasma Copeptin, A Unifying Factor behind the Metabolic Syndrome.
J Clin Endocrinol Metab. 2011 Jul;96(7):E1065-72.




Narayan H, Dhillon OS, Quinn P, Struck J, Squire IB, Davies JE, Ng LL.
C-Terminal Provasopressin (Copeptin) as Prognostic Marker after Acute Non ST Elevation Myocardial Infarction - Leicester Acute Myocardial Infarction Peptide II (LAMP II) study.
Clin Sci (Lond). 2011 Jul 1;121(2):79-89


Klip IT, Voors AA, Anker SD, Hillege HL, Struck J, Squire I, van Veldhuisen DJ, Dickstein K; for the OPTIMAAL investigators.
Prognostic value of mid-regional pro-adrenomedullin in patients with heart failure after an acute myocardial infarction.
Heart. 2011 Jun;97(11):892-898.


Bhandari SS, Davies JE, Struck J, Ng LL.
Influence of confounding factors on plasma mid-regional pro-adrenomedullin and mid-regional pro-A-type natriuretic peptide concentrations in healthy individuals.
Biomarkers. 2011 May;16(3):281-7.



Elmas E, Doesch C, Fluechter S, Freundt M, Weiss C, Lang S, Kälsch T, Haghi D, Papassotiriou J, Kunde J, Schoenberg SO, Borggrefe M, Papavassiliu T.
Midregional pro-atrial natriuretic peptide: a novel marker of myocardial fibrosis in patients with hypertrophic cardiomyopathy.
Int J Cardiovasc Imaging. 2011 Apr;27(4):547-56




Edelmann F, Stahrenberg R, Polzin F, Kockskämper A, Düngen HD, Duvinage A, Binder L, Kunde J, Scherer M, Gelbrich G, Hasenfuß G, Pieske B, Wachter R, Herrmann-Lingen C.
Impaired physical quality of life in patients with diastolic dysfunction associates more strongly with neurohumoral activation than with echocardiographic parameters Quality of life in diastolic dysfunction.
Am Heart J. 2011 Apr;161(4):797-804.


Sinning CR, Sinning JM, Schulz A, Schnabel RB, Lubos E, Wild PS, Papassotiriou J, Bergmann A, Blankenberg S, Munzel T, Bickel C; the AtheroGene Study Investigators.
Association of Serum Procalcitonin With Cardiovascular Prognosis in Coronary Artery Disease.
Circ J. 2011 Apr 25;75(5):1184-1191.




Al-Omari MA, Khaleghi M, Mosley TH Jr, Morgenthaler NG, Struck J, Bergmann A, Kullo IJ.
Plasma C-terminal pro-endothelin-1 is associated with left ventricular mass index and aortic root diameter in African-American adults with hypertension.
J Hum Hypertens. 2011 Feb;25(2):106-13.



Jankowska EA, Filippatos GS, von Haehling S, Papassotiriou J, Morgenthaler NG, Cicoira M, Schefold JC, Rozentryt P, Ponikowska B, Doehner W, Banasiak W, Hartmann O, Struck J, Bergmann A, Anker SD, Ponikowski P.
Identification of chronic heart failure patients with a high 12-month mortality risk using biomarkers including plasma C-terminal pro-endothelin-1.
PLoS One. 2011 Jan 17;6(1):e14506.


Maeder MT, Brutsche MH, Christ A, Staub D, Noveanu M, Breidthardt T, Schaub N, Potocki M, Reichlin T, Morgenthaler NG, Bergmann A, Mueller C.
Midregional pro-A-type natriuretic peptide for the evaluation of exercise intolerance.
Int J Cardiol. 2010 Nov 19;145(2):326-8.


Potocki M, Breidthardt T, Mueller A, Reichlin T, Socrates T, Arenja N, Reiter M, Morgenthaler NG, Bergmann A, Noveanu M, Buser PT, Mueller C.
Copeptin and risk stratification in patients with acute dyspnea.
Crit Care. 2010 Nov 24;14(6):R213.


Torgersen C, Luckner G, Morgenthaler NG, Jochberger S, Schmittinger CA, Wenzel V, Hasibeder WR, Grander W, Dünser MW.
Plasma copeptin levels before and during exogenous arginine vasopressin infusion in patients with advanced vasodilatory shock.
Minerva Anestesiol. 2010 Nov;76(11):905-12.


Habib A, Al-Omari MA, Khaleghi M, Morgenthaler NG, Struck J, Bergmann A, Mosley TH, Turner ST, Kullo IJ.
Plasma C-Terminal Pro-Endothelin-1 Is Associated With Target-Organ Damage in African Americans With Hypertension.
Am J Hypertens. 2010 Nov;23(11):1204-8.


Walter T, Brueckmann M, Lang S, Sauer T, Fiedler E, Papassotiriou J, Behnes M, Elmas E, Borggrefe M, Bertsch T.
Comparison of long-term prognostic value of N-terminal-proBNP and midregional-pro-adrenomedullin in patients with acute myocardial infarction.
Clin Lab. 2010;56(7-8):303-9.

 
Maeder MT, Brutsche MH, Arenja N, Socrates T, Reiter M, Meissner J, Staub D, Morgenthaler NG, Bergmann A, Mueller C.
Biomarkers and Peak Oxygen Uptake in Patients with Chronic Lung Disease.
Respiration. 2010;80(6):543-52.


Dhillon OS, Khan SQ, Narayan HK, Ng KH, Struck J, Quinn PA, Morgenthaler NG, Squire IB, Davies JE, Bergmann A, Ng LL.
Prognostic value of mid-regional pro-adrenomedullin levels taken on admission and discharge in non-ST-elevation myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) II study.
J Am Coll Cardiol. 2010 Jul 6;56(2):125-33.


Darzy KH, Dixit KC, Shalet SM, Morgenthaler NG, Brabant G.
Circadian Secretion Pattern of Copeptin, the C-Terminal Vasopressin Precursor Fragment.
Clin Chem. 2010 Jul;56(7):1190-1.


Kelly D, Khan SQ, Dhillon O, Quinn P, Struck J, Squire IB, Davies JE, Ng LL.
Procalcitonin as a prognostic marker in patients with acute myocardial infarction.
Biomarkers. 2010 Jun;15(4):325-31


Kuster GM, Nietlispach F, Kiowski W, Schindler R, Bernheim A, Schuetz P, Mueller B, Morgenthaler NG, Rüter F, Riesen W, Rickli H, Brunner-La Rocca HP.
Role of RAS inhibition in the regulation of Cu/Zn-SOD in the cardiac and peripheral arterial beds in humans.
Clin Pharmacol Ther. 2010 Jun;87(6):686-92.






von Haehling S, Filippatos GS, Papassotiriou J, Cicoira M, Jankowska EA, Doehner W, Rozentryt P, Vassanelli C, Struck J, Banasiak W, Ponikowski P, Kremastinos D, Bergmann A, Morgenthaler NG, Anker SD.
Mid-regional pro-adrenomedullin as a novel predictor of mortality in patients with chronic heart failure.
Eur J Heart Fail. 2010 May;12(5):484-91.
 

Truong QA, Siegel E, Karakas M, Januzzi JL Jr, Bamberg F, Mahabadi AA, Dasdemir S, Brady TJ, Bergmann A, Kunde J, Nagurney JT, Hoffmann U, Koenig W.
Relation of natriuretic peptides and midregional proadrenomedullin to cardiac chamber volumes by computed tomography in patients without heart failure: from the ROMICAT Trial.
Clin Chem. 2010 Apr;56(4):651-60.



Maeder MT, Staub D, Brutsche MH, Arenja N, Socrates T, Reiter M, Meissner J, Morgenthaler NG, Bergmann A, Struck J, Mueller C.
Copeptin Response to Clinical Maximal Exercise Tests.
Clin Chem. 2010 Apr;56(4):674-6.

 
Masson S, Latini R, Carbonieri E, Moretti L, Rossi MG, Ciricugno S, Milani V, Marchioli R, Struck J, Bergmann A, Maggioni AP, Tognoni G, Tavazzi L; on behalf of the GISSI-HF Investigators.
The predictive value of stable precursor fragments of vasoactive peptides in patients with chronic heart failure: data from the GISSI-heart failure (GISSI-HF) trial.
Eur J Heart Fail. 2010 Apr;12(4):338-347.
Editorial:
Yandle TG, Troughton RW.
Improving risk stratification in heart failure: a role for new biomarkers?
Eur J Heart Fail. 2010 Apr;12(4):315-8.
 


Potocki M, Breidthardt T, Reichlin T, Hartwiger S, Morgenthaler NG, Bergmann A, Noveanu M, Freidank H, Taegtmeyer AB, Wetzel K, Boldanova T, Stelzig C, Bingisser R, Christ M, Mueller C.
Comparison of midregional pro-atrial natriuretic peptide with N-terminal pro-B-type natriuretic peptide in the diagnosis of heart failure.
J Intern Med. 2010 Jan;267(1):119-29.


Miller WL, Hartman KA, Hodge DO, Hartman S, Struck J, Morgenthaler NG, Bergmann A, Jaffe AS.
Response of novel biomarkers to BNP infusion in patients with decompensated heart failure: a multimarker paradigm.
J Cardiovasc Transl Res. 2009 Dec;2(4):526-35.


Bhandari SS, Davies JE, Struck J, Ng LL. 
The midregional portion of proadrenomedullin is an independent predictor of left ventricular mass index in hypertension.
Metabolism. 2010 Jan;59(1):7-13.


Neuhold S, Huelsmann M, Strunk G, Struck J, Adlbrecht C, Gouya G, Elhenicky M, Pacher R.
Prognostic Value of Emerging Neurohormones in Chronic Heart Failure during Optimization of Heart Failure-Specific Therapy.
Clin Chem. 2010 Jan;56(1):121-6.


Endothelial markers may link kidney function to cardiovascular events in type 2 diabetes mellitus.
Diabetes Care. 2009 Oct;32(10):1890-5.



Al-Omari MA, Khaleghi M, Mosley TH Jr, Turner ST, Morgenthaler NG, Struck J, Bergmann A, Kullo IJ.
Mid-Regional Pro-Adrenomedullin Is Associated With Pulse Pressure, Left Ventricular Mass, and Albuminuria in African Americans With Hypertension.
Am J Hypertens. 2009 Aug;22(8):860-6


 
Potocki M, Breidthardt T, Reichlin T, Morgenthaler NG, Bergmann A, Noveanu M, Schaub N, Uthoff H, Freidank H, Buser L, Bingisser R, Christ M, Mebazaa A, Mueller C.
Midregional pro-Adrenomedullin in addition to B-type natriuretic peptides in the risk stratification of patients with acute dyspnea: an observational study.
Crit Care. 2009 Jul 23;13(4):R122.


Melander O, Newton-Cheh C, Almgren P, Hedblad B, Berglund G, Engström G, Persson M, Smith JG, Magnusson M, Christensson A, Struck J, Morgenthaler NG, Bergmann A, Pencina MJ, Wang TJ.
Novel and conventional biomarkers for prediction of incident cardiovascular events in the community.
JAMA. 2009 Jul 1;302(1):49-57.
Comment in:
Shah SH, de Lemos JA.
Biomarkers and cardiovascular disease: determining causality and quantifying contribution to risk assessment.
JAMA. 2009 Jul 1;302(1):92-3.


 


Gombos T, Förhécz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, Morgenthaler NG, Jánoskuti L, Prohászka Z.
Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure.
Inflamm Res. 2009 Jun;58(6):298-305.


 
Voors AA, von Haehling S, Anker SD, Hillege HL, Struck J, Hartmann O, Bergmann A, Squire I, van Veldhuisen DJ, Dickstein K; for the OPTIMAAL investigators.
C-terminal provasopressin (copeptin) is a strong prognostic marker in patients with heart failure after an acute myocardial infarction: results from the OPTIMAAL study.
Eur Heart J. 2009 May;30(10):1187-94


Moertl D, Berger R, Struck J, Gleiss A, Hammer A, Morgenthaler NG, Bergmann A, Huelsmann M, Pacher R.
Comparison of midregional pro-atrial and B-type natriuretic peptides in chronic heart failure: influencing factors, detection of left ventricular systolic dysfunction, and prediction of death.
J Am Coll Cardiol. 2009 May 12;53(19):1783-90.


Maeder MT, Brutsche MH, Staub D, Morgenthaler NG, Bergmann A, Noveanu M, Laule K, Breidthardt T, Christ A, Klima T, Reichlin T, Potocki M, Mueller C.
B-type natriuretic peptide and C-terminal-pro-endothelin-1 for the prediction of severely impaired peak oxygen consumption.
J Intern Med. 2009 May;265(5):604-15


Khaleghi M, Al-Omari MA, Kondragunta V, Morgenthaler NG, Struck J, Bergmann A, Mosley TH, Kullo IJ.
Relation of plasma midregional proatrial natriuretic peptide to target organ damage in adults with systemic hypertension.
Am J Cardiol. 2009 May 1;103(9):1255-60.



Clodi M, Resl M, Stelzeneder D, Pacini G, Tura A, Mörtl D, Struck J, Morgenthaler NG, Bergmann A, Riedl M, Anderwald-Stadler M, Luger A, Pacher R, Hülsmann M.
Interactions of Glucose Metabolism and Chronic Heart Failure.
Exp Clin Endocrinol Diabetes. 2009 Mar;117(3):99-106.


 



Khaleghi M, Saleem U, Morgenthaler NG, Turner ST, Bergmann A, Struck J, Mosley TH, Kullo IJ.
Plasma Midregional Pro-atrial Natriuretic Peptide Is Associated With Blood Pressure Indices and Hypertension Severity in Adults With Hypertension.
Am J Hypertens. 2009 Apr;22(4):425-31


Adlbrecht C, Hülsmann M, Strunk G, Berger R, Mörtl D, Struck J, Morgenthaler NG, Bergmann A, Jakowitsch J, Maurer G, Lang IM, Pacher R.
Prognostic value of plasma midregional pro-adrenomedullin and C-terminal-pro-endothelin-1 in chronic heart failure outpatients.
Eur J Heart Fail. 2009 Apr;11(4):361-6



Bhandari SS, Loke I, Davies JE, Squire IB, Struck J, Ng LL.
Gender and renal function influence plasma levels of copeptin in healthy individuals.
Clin Sci (Lond). 2009 Feb;116(3):257-63



Dieplinger B, Gegenhuber A, Struck J, Poelz W, Langsteger W, Haltmayer M, Mueller T.
Chromogranin A and C-terminal endothelin-1 precursor fragment add independent prognostic information to amino-terminal proBNP in patients with acute destabilized heart failure.
Clin Chim Acta. 2009 Feb;400(1-2):91-6


Staub D, Morgenthaler NG, Buser C, Breidthardt T, Potocki M, Noveanu M, Reichlin T, Bergmann A, Mueller C.
Use of copeptin in the detection of myocardial ischemia.
Clin Chim Acta. 2009 Jan;399(1-2):69-73


Kelly D, Squire IB, Khan SQ, Quinn P, Struck J, Morgenthaler NG, Davies JE, Ng LL.
C-Terminal Provasopressin (Copeptin) is Associated With Left Ventricular Dysfunction, Remodeling, and Clinical Heart Failure in Survivors of Myocardial Infarction.
J Card Fail. 2008 Nov;14(9):739-45



Neuhold S, Huelsmann M, Strunk G, Stoiser B, Struck J, Morgenthaler NG, Bergmann A, Moertl D, Berger R, Pacher R.
Comparison of copeptin, B-type natriuretic peptide, and amino-terminal pro-B-type natriuretic peptide in patients with chronic heart failure: prediction of death at different stages of the disease.
J Am Coll Cardiol. 2008 Jul 22;52(4):266-72



Khan SQ, Dhillon, O, Kelly D, Squire I, Struck J, Quinn P, Morgenthaler N, Bergmann A, Davies J, Ng LL.
Plasma N-Terminal B-Type Natriuretic Peptide as an Indicator of Long-Term Survival After Acute Myocardial Infarction: Comparison With Plasma Midregional Pro-Atrial Natriuretic Peptide: The LAMP (Leicester Acute Myocardial Infarction Peptide) Study
J Am Coll Cardiol. 2008 May 13;51(19):1857-64


Morgenthaler NG, Struck J, Jochberger S, Dünser MW.
Copeptin: clinical use of a new biomarker.
Trends Endocrinol Metab. 2008 Mar;19(2):43-9


Comparison of midregional pro-atrial natriuretic Peptide with N-terminal pro-B-type natriuretic Peptide in predicting survival in patients with chronic heart failure.
J Am Coll Cardiol. 2007 Nov 13;50(20):1973-80




Khan SQ, Dhillon O, Struck J, Quinn P, Morgenthaler NG, Squire IB, Davies JE, Bergmann A, Ng LL.
C-terminal pro-endothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study.
Am Heart J. 2007 Oct;154(4):736-42



Elmas E, Lang S, Dempfle CE, Kälsch T, Papassotiriou J, Morgenthaler NG, Borggrefe M, Brueckmann M.
Diagnostic performance of mid-regional pro-adrenomedullin as an analyte for the exclusion of left ventricular dysfunction.
Int J Cardiol. 2008 Aug 1;128(1):107-11

 
 
Midregional proadrenomedullin reflects cardiac dysfunction in haemodialysis patients with cardiovascular disease.
Nephrol Dial Transplant. 2007 Aug;22(8):2263-8


 
Chi Lim S, Morgenthaler NG, Subramaniam T, Wu YS, Goh SK, Sum CF.
The relationship between adrenomedullin, metabolic factors and vascular function in individuals with type 2 diabetes mellitus.
Diabetes Care. 2007 Jun;30(6):1513-9

C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study.
Circulation. 2007 Apr 24;115(16):2103-10
 
Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study.
J Am Coll Cardiol. 2007 Apr 10;49(14):1525-32
 
Comparative evaluation of B-type natriuretic peptide, mid-regional pro-A-type natriuretic peptide, mid-regional pro-adrenomedullin, and Copeptin to predict 1-year mortality in patients with acute destabilized heart failure.
J Card Fail. 2007 Feb;13(1):42-9
 
Use of midregional proadrenomedullin in the detection of myocardial ischaemia.
Eur J Clin Invest. 2007 Jan;37(1):83-4.
 
Copeptin, a fragment of the vasopressin precursor, as a novel predictor of outcome in heart failure.
Eur J Clin Invest. 2006 Nov;36(11):771-8
 
Midregional pro-A-type natriuretic peptide measurements for diagnosis of acute destabilized heart failure in short-of-breath patients: comparison with B-type natriuretic peptide (BNP) and amino-terminal proBNP.
Clin Chem. 2006 May;52(5):827-31
 
Proteolytic processing pattern of the endothelin-1 precursor in vivo.
Peptides. 2005 Dec;26(12):2482-6
 
Copeptin, a stable peptide derived from the vasopressin precursor, is elevated in serum of sepsis patients.
Peptides. 2005 Dec;26(12):2500-4
 
Use of pro-atrial natriuretic peptide in the detection of myocardial ischaemia.
Eur J Clin Invest. 2005 Jul;35(7):450-6
 
Identification of an Adrenomedullin precursor fragment in plasma of sepsis patients.
Peptides. 2004 Aug;25(8):1369-72
 
 
 
Schilddrüse
 
 
Kratzsch J, Petzold A, Raue F, Reinhardt W, Brocker-Preuss M, Görges R, Mann K, Karges W, Morgenthaler N, Luster M, Reiners C, Thiery J, Dralle H, Fuhrer D.
Basal and Stimulated Calcitonin and Procalcitonin by Various Assays in Patients With and Without Medullary Thyroid Cancer.
Clin Chem. 2011 Mar;57(3):467-474


Eckstein A, Loesch C, Glowacka D, Schott M, Mann K, Esser J, Morgenthaler NG.
Euthyroid and primarily hypothyroid patients develop milder and significantly more asymmetric Graves ophthalmopathy.
Br J Ophthalmol. 2009 Aug;93(8):1052-6.


Eckstein AK, Lax H, Lösch C, Glowacka D, Plicht M, Mann K, Esser J, Morgenthaler NG.
Patients with severe Graves' ophthalmopathy have a higher risk of relapsing hyperthyroidism and are unlikely to remain in remission.
Clin Endocrinol (Oxf). 2007 Oct;67(4):607-12


Improved prediction of relapse of Graves' thyrotoxicosis by combined determination of TSH receptor and thyroperoxidase antibodies.
Horm Metab Res. 2007 Jan;39(1):56-61
 
 
Stimulating and blocking thyroid-stimulating hormone (TSH) receptor autoantibodies from patients with Graves' disease and autoimmune hypothyroidism have very similar concentration, TSH receptor affinity, and binding sites.
J Clin Endocrinol Metab. 2007 Mar;92(3):1058-65
 
 
Thyrotropin receptor autoantibodies are independent risk factors for Graves' ophthalmopathy and help to predict severity and outcome of the disease.
J Clin Endocrinol Metab. 2006 Sep;91(9):3464-70
 
 
Graves' disease and Hashimoto's thyroiditis in monozygotic twins: case study as well as transcriptomic and immunohistological analysis of thyroid tissues.
Eur J Endocrinol. 2006 Jan;154(1):13-20
 
 
Relevance of TSH receptor stimulating and blocking autoantibody measurement for the prediction of relapse in Graves' disease.
Horm Metab Res. 2005 Dec;37(12):741-4
 
 
 
Pro-A-type and N-terminal pro-B-type natriuretic peptides in different thyroid function states.
Swiss Med Wkly. 2005 Sep 17;135(37-38):549-54
 
Thyrotropin receptor autoantibodies in Graves' disease.
Trends Endocrinol Metab. 2005 Jul;16(5):243-8
 
 
TRAK-Bestimmung: Aktuelles für die klinische Praxis. Determination of TSH Receptor Autoantibodies: Current Recommendations for the Clinical Practice
Der Nuklearmediziner 2005;28:11-17
 
 
Expression of the sodium iodide symporter in differentiated thyroid cancer: clinical evidence.
Nuklearmedizin. 2005;44(3):86-93
 
 
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Mol Endocrinol. 2004 Dec;18(12):3020-34
 
 
Clinical results of anti-inflammatory therapy in Graves' ophthalmopathy and association with thyroidal autoantibodies.
Clin Endocrinol (Oxf). 2004 Nov;61(5):612-8
 
 
Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor.
Clin Exp Immunol. 2004 Apr;136(1):129-36
 
 
Levels of autoantibodies against human TSH receptor predict relapse of hyperthyroidism in Graves' disease.
Horm Metab Res. 2004 Feb;36(2):92-6
 
Stimulation of thyroid-stimulating hormone (TSH) receptor antibody production following painless thyroiditis.
Clin Endocrinol (Oxf). 2004 Jan;60(1):49-53
 
 
The effect of thyrotropin-receptor blocking antibodies on stimulating autoantibodies from patients with Graves' disease.
Thyroid. 2003 Dec;13(12):1153-61
 
 
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity.
Biochem Biophys Res Commun. 2002 Dec 20;299(5):891-6
 
 
Detection of low titre TBII in patients with Graves' disease using recombinant human TSH receptor.
Clin Endocrinol (Oxf). 2002 Aug;57(2):193-8
 
 
Low frequency of autoantibodies to the human Na(+)/I(-) symporter in patients with autoimmune thyroid disease.
J Clin Endocrinol Metab. 2000 Dec;85(12):4630-4
 
Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine levels: prevalence, natural history, and thyrotropin receptor antibody levels.
Thyroid. 2000 Dec;10(12):1093-100
 
 
[Clinical implications of a new TSH receptor antibody assay (DYNOtest TRAKhuman) in autoimmune thyroid diseases]
Nuklearmedizin. 2000;39(1):14-8
 
Development of a luminescent bioassay for thyroid stimulating antibodies.
J Clin Endocrinol Metab. 1999 Jan;84(1):374-7
 
Application of a bioassay with CHO cells for the routine detection of stimulating and blocking autoantibodies to the TSH-receptor.
Horm Metab Res. 1998 Mar;30(3):162-8
 
 
 

 

 
Endokrinologie
 

Abbasi A, Corpeleijn E, Meijer E, Postmus D, Gansevoort RT, Gans RO, Struck J, Hillege HL, Stolk RP, Navis G, Bakker SJ.
Sex differences in the association between plasma copeptin and incident type 2 diabetes: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study.
Diabetologia. 2012 Jul;55(7):1963-70


Schulte J.
Peroxiredoxin 4: a multifunctional biomarker worthy of further exploration.
BMC Med. 2011 Dec 23;9(1):137.


Benzing J, Wellmann S, Achini F, Letzner J, Burkhardt T, Beinder E, Morgenthaler NG, Haagen U, Bucher HU, Bührer C, Lapaire O, Szinnai G.
Plasma Copeptin in Preterm Infants: A Highly Sensitive Marker of Fetal and Neonatal Stress.
J Clin Endocrinol Metab. 2011 Jun;96(6):E982-5


Fenske W, Quinkler M, Lorenz D, Zopf K, Haagen U, Papassotiriou J, Pfeiffer AF, Fassnacht M, Störk S, Allolio B.
Copeptin in the Differential Diagnosis of the Polydipsia-Polyuria Syndrome--Revisiting the Direct and Indirect Water Deprivation Tests.
J Clin Endocrinol Metab. 2011 May;96(5):1506-15.


Hew-Butler T, Hoffman MD, Stuempfle KJ, Rogers IR, Morgenthaler NG, Verbalis JG.
Changes in Copeptin and Bioactive Vasopressin in Runners With and Without Hyponatremia.
Clin J Sport Med. 2011 May;21(3):211-217.


Balanescu S, Kopp P, Gaskill MB, Morgenthaler NG, Schindler C, Rutishauser J.
Correlation of Plasma Copeptin and Vasopressin Concentrations in Hypo-, Iso-, and Hyperosmolar States.
J Clin Endocrinol Metab. 2011 Apr;96(4):1046-52



Katan M, Nigro N, Fluri F, Schuetz P, Morgenthaler NG, Jax F, Meckel S, Gass A, Bingisser R, Steck A, Kappos L, Engelter S, Müller B, Christ-Crain M.
Stress hormones predict cerebrovascular re-events after transient ischemic attacks.
Neurology. 2011 Feb 8;76(6):563-6.


Wellmann S, Benzing J, Cippà G, Admaty D, Creutzfeldt R, Mieth RA, Beinder E, Lapaire O, Morgenthaler NG, Haagen U, Szinnai G, Bührer C, Bucher HU.
High Copeptin Concentrations in Umbilical Cord Blood after Vaginal Delivery and Birth Acidosis.
J Clin Endocrinol Metab. 2010 Nov;95(11):5091-6.


Mellbin LG, Rydén L, Brismar K, Morgenthaler NG, Ohrvik J, Catrina SB.
Copeptin, IGFBP-1, and Cardiovascular Prognosis in Patients With Type 2 Diabetes and Acute Myocardial Infarction: A report from the DIGAMI 2 trial.
Diabetes Care. 2010 Jul;33(7):1604-6.

 
 


Maeder MT, Staub D, Brutsche MH, Arenja N, Socrates T, Reiter M, Meissner J, Morgenthaler NG, Bergmann A, Struck J, Mueller C.
Copeptin Response to Clinical Maximal Exercise Tests.
Clin Chem. 2010 Apr;56(4):674-6.

Kleindienst A, Brabant G, Morgenthaler NG, Dixit KC, Parsch H, Buchfelder M.
Following brain trauma, copeptin, a stable peptide derived from the AVP precusor, does not reflect osmoregulation but correlates with injury severity.
Acta Neurochir Suppl. 2010;106:221-4.


Jochberger S, Dörler J, Luckner G, Mayr VD, Wenzel V, Ulmer H, Morgenthaler NG, Hasibeder WR, Dünser MW.
The vasopressin and copeptin response to infection, severe sepsis, and septic shock.
Crit Care Med. 2009 Feb;37(2):476-82


Fenske W, Störk S, Blechschmidt A, Maier SG, Morgenthaler NG, Allolio B.
Copeptin in the differential diagnosis of hyponatremia.
J Clin Endocrinol Metab. 2009 Jan;94(1):123-9



Katan M, Morgenthaler N, Widmer I, Puder JJ, König C, Müller B, Christ-Crain M.
Copeptin, a stable peptide derived from the vasopressin precursor, correlates with the individual stress level.
Neuro Endocrinol Lett. 2008 Jun;29(3):341-6.



Morgenthaler NG, Struck J, Jochberger S, Dünser MW.
Copeptin: clinical use of a new biomarker.
Trends Endocrinol Metab. 2008 Mar;19(2):43-9



Westermann I, Dünser MW, Haas T, Jochberger S, Luckner G, Mayr VD, Wenzel V, Stadlbauer KH, Innerhofer P, Morgenthaler N, Hasibeder WR, Voelckel WG.
Endogenous vasopressin and copeptin response in multiple trauma patients.
Shock. 2007 Dec;28(6):644-649



Klose M, Juul A, Struck J, Morgenthaler NG, Kosteljanetz M, Feldt-Rasmussen U.
Acute and long-term pituitary insufficiency in traumatic brain injury: a prospective single-centre study.
Clin Endocrinol (Oxf). 2007 Oct;67(4):598-606


 
Szinnai G, Morgenthaler NG, Berneis K, Struck J, Müller B, Keller U, Christ-Crain M.
Changes in plasma copeptin, the C-terminal portion of arginine vasopressin during water deprivation and excess in healthy subjects.
J Clin Endocrinol Metab. 2007 Oct;92(10):3973-3978


Anterior and posterior pituitary function testing with simultaneous insulin tolerance test and a novel copeptin assay.
J Clin Endocrinol Metab. 2007 Jul;92(7):2640-3




Chi Lim S, Morgenthaler NG, Subramaniam T, Wu YS, Goh SK, Sum CF.
The relationship between adrenomedullin, metabolic factors and vascular function in individuals with type 2 diabetes mellitus.
Diabetes Care. 2007 Jun;30(6):1513-9
  
 
 
Neurodegeneration
 
 
Schneider P, Buerger K, Teipel S, Uspenskaya O, Hartmann O, Hansson O, Minthon L, Rujescu D, Moeller HJ, Zetterberg H, Blennow K, Ernst A, Bergmann A, Hampel H.
Antihypertensive Therapy Is Associated with Reduced Rate of Conversion to Alzheimer's Disease in Midregional Proatrial Natriuretic Peptide Stratified Subjects with Mild Cognitive Impairment.
Biol Psychiatry. 2011 Jul 15;70(2):145-51.


Buerger K, Uspenskaya O, Hartmann O, Hansson O, Minthon L, Blennow K, Moeller HJ, Teipel SJ, Ernst A, Bergmann A, Hampel H.
Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment.
J Clin Psychiatry. 2011 Apr;72(4):556-63


Buerger K, Ernst A, Ewers M, Uspenskaya O, Omerovic M, Morgenthaler NG, Knauer K, Bergmann A, Hampel H.
Blood-Based Microcirculation Markers in Alzheimer's Disease-Diagnostic Value of Midregional Pro-atrial Natriuretic Peptide/C-terminal Endothelin-1 Precursor Fragment Ratio.
Biol Psychiatry. 2009 Jun 1;65(11):979-84



Ernst A, Morgenthaler NG, Buerger K, Dodel R, Noelker C, Sommer N, Schwarz M, Koehrle J, Bergmann A, Hampel H.
Procalcitonin is elevated in the cerebrospinal fluid of patients with dementia and acute neuroinflammation.
J Neuroimmunol. 2007 Sep;189(1-2):169-74


Decreased serum amyloid beta(1-42) autoantibody levels in Alzheimer's disease, determined by a newly developed immuno-precipitation assay with radiolabeled amyloid beta(1-42) peptide.
Biol Psychiatry. 2005 Apr 1;57(7):813-6


Sonstige



Ulm L, Ohlraun S, Harms H, Hoffmann S, Klehmet J, Ebmeyer S, Hartmann O, Meisel C, Anker SD, Meisel A.
STRoke Adverse outcome is associated WIth NoSocomial Infections (STRAWINSKI): procalcitonin ultrasensitive-guided antibacterial therapy in severe ischaemic stroke patients - rationale and protocol for a randomized controlled trial.
Int J Stroke. 2013 Oct;8(7):598-603


Nickel CH, Messmer AS, Geigy N, Misch F, Mueller B, Dusemund F, Hertel S, Hartmann O, Giersdorf S, Bingisser R.
Stress markers predict mortality in patients with nonspecific complaints presenting to the emergency department and may be a useful risk stratification tool to support disposition planning.
Acad Emerg Med. 2013 Jul;20(7):670-9.


Boertien WE, Riphagen IJ, Drion I, Alkhalaf A, Bakker SJ, Groenier KH, Struck J, de Jong PE, Bilo HJ, Kleefstra N, Gansevoort RT.
Copeptin, a surrogate marker for arginine vasopressin, is associated with declining glomerular filtration in patients with diabetes mellitus (ZODIAC-33).
Diabetologia. 2013 Aug;56(8):1680-1688.


Enhörning S, Bankir L, Bouby N, Struck J, Hedblad B, Persson M, Morgenthaler NG, Nilsson PM, Melander O.
Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmö Diet and Cancer Study cardiovascular cohort.
Int J Obes (Lond). 2013 Apr;37(4):598-603


De Marchis GM, Katan M, Weck A, Brekenfeld C, Mattle HP, Buhl D, Müller B, Christ-Crain M, Arnold M.
Copeptin and risk stratification in patients with ischemic stroke and transient ischemic attack: The CoRisk Study.
Int J Stroke. 2013 Apr;8(3):214-8


Fedorowski A, Burri P, Struck J, Juul-Möller S, Melander O.
Novel cardiovascular biomarkers in unexplained syncopal attacks: the SYSTEMA cohort.
J Intern Med. 2013 Apr;273(4):359-67


Wuttke A, Dixit KC, Szinnai G, Werth SC, Haagen U, Christ-Crain M, Morgenthaler N, Brabant G.
Copeptin as a marker for arginine-vasopressin/antidiuretic hormone secretion in the diagnosis of paraneoplastic syndrome of inappropriate ADH secretion.
Endocrine. 2013 Mar 12.



Rudovich N, Pivovarova O, Traberth A, Sparwasser A, Weickert MO, Bernigau W, Birkenfeld AL, Arafat AM, Bergmann A, Pfeiffer AF.
Acarbose treatment enhances mid-regional pro-atrial natriuretic peptide concentrations in non-diabetic individuals: further evidence for a common cardiometabolic pathway?
Diabetologia. 2012 Dec;55(12):3392-5


Boertien WE, Meijer E, Zittema D, van Dijk MA, Rabelink TJ, Breuning MH, Struck J, Bakker SJ, Peters DJ, de Jong PE, Gansevoort RT.
Copeptin, a surrogate marker for vasopressin, is associated with kidney function decline in subjects with autosomal dominant polycystic kidney disease.
Nephrol Dial Transplant. 2012 Nov;27(11):4131-7.



Meisel A, Meisel C, Harms H, Hartmann O, Ulm L.
Predicting post-stroke infections and outcome with blood-based immune and stress markers.
Cerebrovasc Dis. 2012;33(6):580-8.


Admaty D, Benzing J, Burkhardt T, Lapaire O, Hegi L, Szinnai G, Morgenthaler NG, Bucher HU, Bührer C, Wellmann S.
Plasma midregional proadrenomedullin in newborn infants: impact of prematurity and perinatal infection.
Pediatr Res. 2012 Jul;72(1):70-6.



Belting M, Almgren P, Manjer J, Hedblad B, Struck J, Wang TJ, Bergmann A, Melander O.
Vasoactive Peptides with Angiogenesis-Regulating Activity Predict Cancer Risk in Males.
Cancer Epidemiol Biomarkers Prev. 2012 Mar;21(3):513-22.


Kleindienst A, Brabant G, Morgenthaler NG, Emtmann I, Scheufler N, Buchfelder M.
The atrial natriuretic peptide does not serve osmoregulation but predicts outcome following brain injury.
Acta Neurochir Suppl. 2012;114:277-81.


Benzing J, Stabile O, Szinnai G, Morgenthaler NG, Schulzke SM, Bührer C, Wellmann S.
Plasma Pro-Endothelin-1 and Respiratory Distress in Newborn Infants.
J Pediatr. 2012 Mar;160(3):517-9.


Nickel CH, Bingisser R, Morgenthaler NG.
The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department.
BMC Med. 2012 Jan 20;10(1):7.



Abbasi A, Corpeleijn E, Postmus D, Gansevoort RT, de Jong PE, Gans RO, Struck J, Hillege HL, Stolk RP, Navis G, Bakker SJ.
Plasma procalcitonin and risk of type 2 diabetes in the general population.
Diabetologia. 2011 Sep;54(9):2463-5.



Nickel CH, Ruedinger J, Misch F, Blume K, Maile S, Schulte J, Köhrle J, Hartmann O, Giersdorf S, Bingisser R.
Copeptin and peroxiredoxin-4 independently predict mortality in patients with nonspecific complaints presenting to the emergency department.
Acad Emerg Med. 2011 Aug;18(8):851-9.



Meijer E, Gansevoort RT, de Jong PE, van der Wal AM, Leonhard WN, de Krey SR, van den Born J, Mulder GM, van Goor H, Struck J, de Heer E, Peters DJ.
Therapeutic potential of vasopressin V2 receptor antagonist in a mouse model for autosomal dominant polycystic kidney disease: optimal timing and dosing of the drug.
Nephrol Dial Transplant. 2011 Aug;26(8):2445-53



Benzing J, Wellmann S, Achini F, Letzner J, Burkhardt T, Beinder E, Morgenthaler NG, Haagen U, Bucher HU, Bührer C, Lapaire O, Szinnai G.
Plasma Copeptin in Preterm Infants: A Highly Sensitive Marker of Fetal and Neonatal Stress.
J Clin Endocrinol Metab. 2011 Jun;96(6):E982-5.


Hew-Butler T, Hoffman MD, Stuempfle KJ, Rogers IR, Morgenthaler NG, Verbalis JG.
Changes in Copeptin and Bioactive Vasopressin in Runners With and Without Hyponatremia.
Clin J Sport Med. 2011 May;21(3):211-217.


Gouya G, Sturm G, Lamina C, Zitt E, Freistätter O, Struck J, Wolzt M, Knoll F, Lins F, Lhotta K, Neyer U, Kronenberg F.
The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic Peptide with mortality in an incident dialysis cohort.
PLoS One. 2011 Mar 7;6(3):e17803.


Meijer E, Bakker SJ, van der Jagt EJ, Navis G, de Jong PE, Struck J, Gansevoort RT.
Copeptin, a Surrogate Marker of Vasopressin, Is Associated with Disease Severity in Autosomal Dominant Polycystic Kidney Disease.
Clin J Am Soc Nephrol. 2011 Feb;6(2):361-8


Katan M, Nigro N, Fluri F, Schuetz P, Morgenthaler NG, Jax F, Meckel S, Gass A, Bingisser R, Steck A, Kappos L, Engelter S, Müller B, Christ-Crain M.
Stress hormones predict cerebrovascular re-events after transient ischemic attacks.
Neurology. 2011 Feb 8;76(6):563-6.


Wellmann S, Benzing J, Cippà G, Admaty D, Creutzfeldt R, Mieth RA, Beinder E, Lapaire O, Morgenthaler NG, Haagen U, Szinnai G, Bührer C, Bucher HU.
High Copeptin Concentrations in Umbilical Cord Blood after Vaginal Delivery and Birth Acidosis.
J Clin Endocrinol Metab. 2010 Nov;95(11):5091-6.

 
Tørring N, Ball S, Wright D, Sarkissian G, Guitton M, Darbouret B.
First trimester screening for trisomy 21 in gestational week 8-10 by ADAM12-S as a maternal serum marker.
Reprod Biol Endocrinol. 2010 Oct 29;8:129.



Katan M, Fluri F, Schuetz P, Morgenthaler NG, Zweifel C, Bingisser R, Kappos L, Steck A, Engelter ST, Müller B, Christ-Crain M.
Midregional pro-atrial natriuretic peptide and outcome in patients with acute ischemic stroke.
J Am Coll Cardiol. 2010 Sep 21;56(13):1045-53.


Darzy KH, Dixit KC, Shalet SM, Morgenthaler NG, Brabant G.
Circadian Secretion Pattern of Copeptin, the C-Terminal Vasopressin Precursor Fragment.
Clin Chem. 2010 Jul;56(7):1190-1.


Mellbin LG, Rydén L, Brismar K, Morgenthaler NG, Ohrvik J, Catrina SB.
Copeptin, IGFBP-1, and Cardiovascular Prognosis in Patients With Type 2 Diabetes and Acute Myocardial Infarction: A report from the DIGAMI 2 trial.
Diabetes Care. 2010 Jul;33(7):1604-6.


Urwyler SA, Schuetz P, Fluri F, Morgenthaler NG, Zweifel C, Bergmann A, Bingisser R, Kappos L, Steck A, Engelter S, Müller B, Christ-Crain M, Katan M.
Prognostic Value of Copeptin. One-Year Outcome in Patients With Acute Stroke.
Stroke. 2010 Jul;41(7):1564-7.


Kuster GM, Nietlispach F, Kiowski W, Schindler R, Bernheim A, Schuetz P, Mueller B, Morgenthaler NG, Rüter F, Riesen W, Rickli H, Brunner-La Rocca HP.
Role of RAS inhibition in the regulation of Cu/Zn-SOD in the cardiac and peripheral arterial beds in humans.
Clin Pharmacol Ther. 2010 Jun;87(6):686-92.


Zweifel C, Katan M, Schuetz P, Siegemund M, Morgenthaler NG, Merlo A, Mueller B, Christ-Crain M.
Copeptin is associated with mortality and outcome in patients with acute intracerebral hemorrhage.
BMC Neurol. 2010 May 26;10(1):34.


 


Vasoactive mediators in patients with acute liver failure treated with albumin dialysis.
Liver Int. 2010 Apr;30(4):634-6.


Meijer E, Bakker SJ, Halbesma N, de Jong PE, Struck J, Gansevoort RT.
Copeptin, a surrogate marker of vasopressin, is associated with microalbuminuria in a large population cohort.
Kidney Int. 2010 Jan;77(1):29-36.
Comment in:
Cirillo M.
Determinants of kidney dysfunction: is vasopressin a new player in the arena?
Kidney Int. 2010 Jan;77(1):5-6.


Katan M, Fluri F, Morgenthaler NG, Schuetz P, Zweifel C, Bingisser R, Müller K, Meckel S, Gass A, Kappos L, Steck AJ, Engelter ST, Müller B, Christ-Crain M.
Copeptin: A novel, independent prognostic marker in patients with ischemic stroke.
Ann Neurol. 2009 Dec 29;66(6):799-808.


Meijer E, Bakker SJ, de Jong PE, Homan van der Heide JJ, van Son WJ, Struck J, Lems SP, Gansevoort RT.
Copeptin, a surrogate marker of vasopressin, is associated with accelerated renal function decline in renal transplant recipients.
Transplantation. 2009 Aug 27;88(4):561-7.
Comment in:
Dünser MW, Schmittinger CA, Torgersen C.
Copeptin and the transplanted kidney: friends or foes?
Transplantation. 2009 Aug 27;88(4):455-6.


Smith JG, Newton-Cheh C, Hedblad B, Struck J, Morgenthaler NG, Bergmann A, Wang TJ, Melander O.
Distribution and Correlates of Midregional Proadrenomedullin in the General Population.
Clin Chem. 2009 Aug;55(8):1593-5.


van Ree RM, de Vries AP, Oterdoom LH, Seelen MA, Gansevoort RT, Schouten JP, Struck J, Navis G, Gans RO, van der Heide JJ, van Son WJ, Bakker SJ.
Plasma procalcitonin is an independent predictor of graft failure late after renal transplantation.
Transplantation. 2009 Jul 27;88(2):279-87.


Saleem U, Khaleghi M, Morgenthaler NG, Bergmann A, Struck J, Mosley TH Jr, Kullo IJ.
Plasma Carboxy-terminal Pro-Vasopressin (Copeptin): A Novel Marker of Insulin Resistance and Metabolic Syndrome.
J Clin Endocrinol Metab. 2009 Jul;94(7):2558-64



Vila G, Riedl M, Maier C, Struck J, Morgenthaler NG, Handisurya A, Prager G, Ludvik B, Clodi M, Luger A.
Plasma MR-proADM Correlates to BMI and Decreases in Relation to Leptin After Gastric Bypass Surgery.
Obesity (Silver Spring). 2009 Jun;17(6):1184-8




Dieplinger B, Mueller T, Kollerits B, Struck J, Ritz E, von Eckardstein A, Haltmayer M, Kronenberg F.
Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study.
Kidney Int. 2009 Feb;75(4):408-14


Sarkissian G, Fergelot P, Lamy PJ, Patard JJ, Culine S, Jouin P, Rioux-Leclercq N, Darbouret B.
Identification of pro-MMP-7 as a serum marker for renal cell carcinoma by use of proteomic analysis.
Clin Chem. 2008 Mar;54(3):574-81.